RT Journal Article
SR Electronic
T1 New insulin preparations: A primer for the clinician
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP S27
OP S33
DO 10.3949/ccjm.83.s1.05
VO 83
IS 5 suppl 1
A1 Meneghini, Luigi
YR 2016
UL http://www.ccjm.org/content/83/5_suppl_1/S27.abstract
AB The importance of glycemic control in preventing the chronic and devastating complications of diabetes is well established. Insulin administration is an important therapeutic option for managing diabetes, particularly for patients with profound insulin deficiency. Many insulin formulations are on the market, including short-acting insulin analogues, inhaled insulin, concentrated insulin, and basal insulin. Each category has a unique onset, peak, and duration of action. This article reviews the differing pharmacokinetic and pharmacodynamic properties and safety and efficacy data, and discusses the implications for clinical practice.