PT - JOURNAL ARTICLE AU - Arce, Karla M. AU - Lin, Yu Kuei AU - Stevens, Tyler AU - Walsh, R. Matthew AU - Hatipoglu, Betul A. TI - Total pancreatectomy and islet cell autotransplantation: Definitive treatment for chronic pancreatitis AID - 10.3949/ccjm.83a.15056 DP - 2016 Jun 01 TA - Cleveland Clinic Journal of Medicine PG - 435--442 VI - 83 IP - 6 4099 - http://www.ccjm.org/content/83/6/435.short 4100 - http://www.ccjm.org/content/83/6/435.full SO - Cleve Clin J Med2016 Jun 01; 83 AB - In appropriately selected patients, total pancreatectomy and islet cell autotransplant controls pain and improves quality of life while often minimizing the development of overt diabetes. Multidisciplinary management and lifelong follow-up help to maximize the benefit of this procedure. This review highlights its history, indications, metabolic outcomes, and future directions.