TY - JOUR T1 - Total pancreatectomy and islet cell autotransplantation: Definitive treatment for chronic pancreatitis JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 435 LP - 442 DO - 10.3949/ccjm.83a.15056 VL - 83 IS - 6 AU - Karla M. Arce AU - Yu Kuei Lin AU - Tyler Stevens AU - R. Matthew Walsh AU - Betul A. Hatipoglu Y1 - 2016/06/01 UR - http://www.ccjm.org/content/83/6/435.abstract N2 - In appropriately selected patients, total pancreatectomy and islet cell autotransplant controls pain and improves quality of life while often minimizing the development of overt diabetes. Multidisciplinary management and lifelong follow-up help to maximize the benefit of this procedure. This review highlights its history, indications, metabolic outcomes, and future directions. ER -