PT - JOURNAL ARTICLE AU - Tavankit Singh AU - Nancy Gupta AU - Naim Alkhouri AU - William D. Carey AU - Ibrahim A. Hanouneh TI - A guide to managing acute liver failure AID - 10.3949/ccjm.83a.15101 DP - 2016 Jun 01 TA - Cleveland Clinic Journal of Medicine PG - 453--462 VI - 83 IP - 6 4099 - http://www.ccjm.org/content/83/6/453.short 4100 - http://www.ccjm.org/content/83/6/453.full SO - Cleve Clin J Med2016 Jun 01; 83 AB - Nearly 2,000 cases of acute liver failure occur each year in the United States. This disease carries a high mortality rate, and early recognition and transfer to a tertiary medical care center with transplant facilities is critical. This article reviews the definition, epidemiology, etiology, and management of acute liver failure.