RT Journal Article
SR Electronic
T1 Alpha-1 antitrypsin deficiency: An underrecognized, treatable cause of COPD
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 507
OP 514
DO 10.3949/ccjm.83a.16031
VO 83
IS 7
A1 James K. Stoller
YR 2016
UL http://www.ccjm.org/content/83/7/507.abstract
AB Alpha-1 antitrypsin deficiency is common but underrecognized. Because delayed diagnosis is thought to be associated with adverse outcomes, clinicians are encouraged to follow available guidelines and test for the disease in all symptomatic adults with fixed airflow obstruction. The weight of available evidence supports the biochemical and clinical efficacy of intravenous augmentation therapy. Promising new therapies are being investigated.