RT Journal Article
SR Electronic
T1 Update on the management of intestinal failure
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 841
OP 848
DO 10.3949/ccjm.83a.15045
VO 83
IS 11
A1 Shishira Bharadwaj
A1 Parul Tandon
A1 John M. Rivas
A1 Anne Furman
A1 Lisa Moccia
A1 Ashley Ratliff
A1 Abdullah Shatnawei
A1 Ezra Steiger
A1 Donald F. Kirby
YR 2016
UL http://www.ccjm.org/content/83/11/841.abstract
AB Intestinal failure is a serious complication of conditions such as inflammatory bowel disease, mesenteric ischemia, and radiation enteritis—and of extensive bowel resection performed because of these diseases. Imbalances of fluids and electrolytes and poor nutritional status manifest as chronic diarrhea or increased ostomy output. Prompt referral to a center specializing in intestinal rehabilitation is key to achieving nutritional homeostasis and, in some cases, can help the patient return to oral food intake. We review the intestinal sequelae of bowel resection and provide an update on intestinal rehabilitation with dietary modification, drug therapy, and parenteral nutrition. We also review current experience with intestinal transplant, a potentially lifesaving option in select patients when intestinal rehabilitation fails or parenteral nutrition causes severe complications.