PT  - JOURNAL ARTICLE
AU  - Khendi White
AU  - Chaitra Mohan
AU  - Michael Rocco
TI  - PCSK9 inhibition: A promise fulfilled?
AID  - 10.3949/ccjm.83.s2.05
DP  - 2016 Nov 01
TA  - Cleveland Clinic Journal of Medicine
PG  - S36--S44
VI  - 83
IP  - 11 suppl 2
4099  - http://www.ccjm.org/content/83/11_suppl_2/S36.short
4100  - http://www.ccjm.org/content/83/11_suppl_2/S36.full
SO  - Cleve Clin J Med2016 Nov 01; 83
AB  - The association of reduced proprotein convertase subtilisin/kexin type 9 (PCSK9) activity with reduced cardiovascular disease (CVD) events—and the need for add-ons to statin therapy to achieve treatment goals— has led to the rapid development and US Food and Drug Administration (FDA) approval of monoclonal antibody therapies to inhibit PCSK9. Now that PCSK9 inhibitors are approved by the FDA for use in certain patients, data from ongoing long-term clinical trials addressing tolerability, safety, and proof of additional reduction in CVD events are eagerly awaited