PT  - JOURNAL ARTICLE
AU  - Jennifer K. Hockings
AU  - Amy L. Pasternak
AU  - Angelika L. Erwin
AU  - Neil T. Mason
AU  - Charis Eng
AU  - J. Kevin Hicks
TI  - Pharmacogenomics: An evolving clinical tool for precision medicine
AID  - 10.3949/ccjm.87a.19073
DP  - 2020 Feb 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 91--99
VI  - 87
IP  - 2
4099  - http://www.ccjm.org/content/87/2/91.short
4100  - http://www.ccjm.org/content/87/2/91.full
SO  - Cleve Clin J Med2020 Feb 01; 87
AB  - Pharmacogenomics, ie, the study of how an individual’s genomic profile influences his or her response to drugs, has emerged as a clinical tool to optimize drug therapy. Certain variants in some genes increase the risk of severe, life-threatening adverse effects from certain drugs. Integrating pharmacogenomics into clinical practice to assist in drug selection and dosing has the potential to improve the outcomes of treatment, reduce the risk of drug-induced morbidity and death, and be cost-effective.