TY - JOUR T1 - Pharmacogenomics: An evolving clinical tool for precision medicine JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 91 LP - 99 DO - 10.3949/ccjm.87a.19073 VL - 87 IS - 2 AU - Jennifer K. Hockings AU - Amy L. Pasternak AU - Angelika L. Erwin AU - Neil T. Mason AU - Charis Eng AU - J. Kevin Hicks Y1 - 2020/02/01 UR - http://www.ccjm.org/content/87/2/91.abstract N2 - Pharmacogenomics, ie, the study of how an individual’s genomic profile influences his or her response to drugs, has emerged as a clinical tool to optimize drug therapy. Certain variants in some genes increase the risk of severe, life-threatening adverse effects from certain drugs. Integrating pharmacogenomics into clinical practice to assist in drug selection and dosing has the potential to improve the outcomes of treatment, reduce the risk of drug-induced morbidity and death, and be cost-effective. ER -