RT Journal Article
SR Electronic
T1 Pharmacogenomics: An evolving clinical tool for precision medicine
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 91
OP 99
DO 10.3949/ccjm.87a.19073
VO 87
IS 2
A1 Jennifer K. Hockings
A1 Amy L. Pasternak
A1 Angelika L. Erwin
A1 Neil T. Mason
A1 Charis Eng
A1 J. Kevin Hicks
YR 2020
UL http://www.ccjm.org/content/87/2/91.abstract
AB Pharmacogenomics, ie, the study of how an individual’s genomic profile influences his or her response to drugs, has emerged as a clinical tool to optimize drug therapy. Certain variants in some genes increase the risk of severe, life-threatening adverse effects from certain drugs. Integrating pharmacogenomics into clinical practice to assist in drug selection and dosing has the potential to improve the outcomes of treatment, reduce the risk of drug-induced morbidity and death, and be cost-effective.