PT - JOURNAL ARTICLE AU - Neelima Penugonda AU - Adam Mohmand-Borkowski AU - James F. Burke TI - Dronedarone for atrial fibrillation: How does it compare with amiodarone? AID - 10.3949/ccjm.78a.10049 DP - 2011 Mar 01 TA - Cleveland Clinic Journal of Medicine PG - 179--185 VI - 78 IP - 3 4099 - http://www.ccjm.org/content/78/3/179.short 4100 - http://www.ccjm.org/content/78/3/179.full SO - Cleve Clin J Med2011 Mar 01; 78 AB - Dronedarone (Multaq), an analogue of amiodarone (Cordarone), was designed to cause fewer adverse effects than the parent compound. Studies have indeed shown dronedarone to be safer than amiodarone, but less effective. Its official indication is to reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation or atrial flutter and other cardiovascular risk factors, reflecting the parameters of its effectiveness in clinical trials.