RT Journal Article SR Electronic T1 Insulin treatment for type 2 diabetes: When to start, which to use JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 332 OP 342 DO 10.3949/ccjm.78a.10051 VO 78 IS 5 A1 Hamaty, Marwan YR 2011 UL http://www.ccjm.org/content/78/5/332.abstract AB In type 2 diabetes mellitus, oral hypoglycemic agents and analogues of glucagon-like peptide-1 provide adequate glycemic control early in the disease. Insulin therapy becomes necessary for those with advanced disease. Further, some experts recommend electively starting insulin therapy in early diabetes. This review addresses practical approaches to insulin therapy, particularly when it is indicated and which regimen to use.