PT - JOURNAL ARTICLE AU - Fernandez, Genaro AU - Spatz, Erica S. AU - Jablecki, Charles AU - Phillips, Paul S. TI - Statin myopathy: A common dilemma not reflected in clinical trials AID - 10.3949/ccjm.78a.10073 DP - 2011 Jun 01 TA - Cleveland Clinic Journal of Medicine PG - 393--403 VI - 78 IP - 6 4099 - http://www.ccjm.org/content/78/6/393.short 4100 - http://www.ccjm.org/content/78/6/393.full SO - Cleve Clin J Med2011 Jun 01; 78 AB - Although statins are remarkably effective, they are still underprescribed because of concerns about muscle toxicity. We review the aspects of statin myopathy that are important to the primary care physician and provide a guide for evaluating patients on statins who present with muscle complaints. We outline the differential diagnosis, the risks and benefits of statin therapy in patients with possible toxicity, and the subsequent treatment options.