PT - JOURNAL ARTICLE AU - Ott, Susan M. TI - What is the optimal duration of bisphosphonate therapy? AID - 10.3949/ccjm.78a.11022 DP - 2011 Sep 01 TA - Cleveland Clinic Journal of Medicine PG - 619--630 VI - 78 IP - 9 4099 - http://www.ccjm.org/content/78/9/619.short 4100 - http://www.ccjm.org/content/78/9/619.full SO - Cleve Clin J Med2011 Sep 01; 78 AB - It is reasonable to stop bisphosphonates after 5 years of use and then to follow patients with markers of bone turnover. As long as the levels of these markers remain reduced, adding an antiresorptive drug does not make physiologic sense.