RT Journal Article SR Electronic T1 Is there a time limit for systemic menopausal hormone therapy? JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 605 OP 612 DO 10.3949/ccjm.83a.15161 VO 83 IS 8 A1 Laura Dorr Lipold A1 Pelin Batur A1 Risa Kagan YR 2016 UL http://www.ccjm.org/content/83/8/605.abstract AB In deciding whether it is time to stop hormone therapy, in addition to the patient’s age we need to consider her preferences, symptoms, quality of life, time since menopause, hysterectomy status, and personal risks of osteoporosis, breast cancer, heart disease, stroke, and venous thromboembolism. This article presents the evidence for and against extending hormone therapy and a guide for making this highly individualized and shared decision.