PT  - JOURNAL ARTICLE
AU  - Nakhoul, Georges
AU  - Simon, James F.
TI  - Anemia of chronic kidney disease: Treat it, but not too aggressively
AID  - 10.3949/ccjm.83a.15065
DP  - 2016 Aug 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 613--624
VI  - 83
IP  - 8
4099  - http://www.ccjm.org/content/83/8/613.short
4100  - http://www.ccjm.org/content/83/8/613.full
SO  - Cleve Clin J Med2016 Aug 01; 83
AB  - Anemia of renal disease is common and is associated with significant morbidity and death. It is mainly caused by a decrease in erythropoietin production in the kidneys and can be partially corrected with erythropoiesis-stimulating agents (ESAs). However, randomized controlled trials have shown that using ESAs to target normal hemoglobin levels can be harmful, and have called into question any benefits of ESA treatment other than avoidance of transfusions.