RT Journal Article
SR Electronic
T1 Anemia of chronic kidney disease: Treat it, but not too aggressively
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 613
OP 624
DO 10.3949/ccjm.83a.15065
VO 83
IS 8
A1 Georges Nakhoul
A1 James F. Simon
YR 2016
UL http://www.ccjm.org/content/83/8/613.abstract
AB Anemia of renal disease is common and is associated with significant morbidity and death. It is mainly caused by a decrease in erythropoietin production in the kidneys and can be partially corrected with erythropoiesis-stimulating agents (ESAs). However, randomized controlled trials have shown that using ESAs to target normal hemoglobin levels can be harmful, and have called into question any benefits of ESA treatment other than avoidance of transfusions.