PT - JOURNAL ARTICLE AU - Ernest Suresh AU - Bo Abrahamsen TI - Denosumab: A novel antiresorptive drug for osteoporosis AID - 10.3949/ccjm.82a.13173 DP - 2015 Feb 01 TA - Cleveland Clinic Journal of Medicine PG - 105--114 VI - 82 IP - 2 4099 - http://www.ccjm.org/content/82/2/105.short 4100 - http://www.ccjm.org/content/82/2/105.full SO - Cleve Clin J Med2015 Feb 01; 82 AB - Denosumab is a novel antiresorptive drug that has been approved for use as a first-line drug for primary and secondary prevention of osteoporotic fractures. The authors discuss the mechanism of action of denosumab, review the evidence for its efficacy and safety in patients with osteoporosis, and offer recommendations for its use in clinical practice.