RT Journal Article SR Electronic T1 Denosumab: A novel antiresorptive drug for osteoporosis JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 105 OP 114 DO 10.3949/ccjm.82a.13173 VO 82 IS 2 A1 Ernest Suresh A1 Bo Abrahamsen YR 2015 UL http://www.ccjm.org/content/82/2/105.abstract AB Denosumab is a novel antiresorptive drug that has been approved for use as a first-line drug for primary and secondary prevention of osteoporotic fractures. The authors discuss the mechanism of action of denosumab, review the evidence for its efficacy and safety in patients with osteoporosis, and offer recommendations for its use in clinical practice.