RT Journal Article
SR Electronic
T1 Dermatology update: The dawn of targeted treatment
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 309
OP 320
DO 10.3949/ccjm.82gr.15002
VO 82
IS 5
A1 Anthony P. Fernandez
YR 2015
UL http://www.ccjm.org/content/82/5/309.abstract
AB During the past several years, targeted therapies have significantly improved outcomes in advanced basal cell carcinoma, psoriasis, and metastatic melanoma. This article reviews how advances in our understanding of the molecular pathogenesis of these diseases led to the development of targeted therapies and how these therapies are improving outcomes. Research is ongoing to address continuing challenges of drug resistance, adverse effects, and how best to use the new medications.