PT - JOURNAL ARTICLE AU - Hanna, Elias B. AU - Glancy, David Luke TI - ST-segment elevation: Differential diagnosis, caveats AID - 10.3949/ccjm.82a.14026 DP - 2015 Jun 01 TA - Cleveland Clinic Journal of Medicine PG - 373--384 VI - 82 IP - 6 4099 - http://www.ccjm.org/content/82/6/373.short 4100 - http://www.ccjm.org/content/82/6/373.full SO - Cleve Clin J Med2015 Jun 01; 82 AB - The differential diagnosis of ST-segment elevation includes four major processes: ST-segment elevation myocardial infarction (STEMI); early repolarization; pericarditis; and ST elevation secondary to an abnormality of the QRS complex (left bundle branch block, left ventricular hypertrophy, or preexcitation). Other processes that may be associated with ST elevation include hyperkalemia, pulmonary embolism, and Brugada syndrome. The clinical setting and specific electrocardiographic criteria often allow identification of the cause. This article reviews ST-T and QRS configurations specific to each diagnosis.