PT  - JOURNAL ARTICLE
AU  - Riane J. Ghamrawi
AU  - Elizabeth Neuner
AU  - Susan J. Rehm
TI  - Ceftaroline fosamil: A super-cephalosporin?
AID  - 10.3949/ccjm.82a.14105
DP  - 2015 Jul 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 437--444
VI  - 82
IP  - 7
4099  - http://www.ccjm.org/content/82/7/437.short
4100  - http://www.ccjm.org/content/82/7/437.full
SO  - Cleve Clin J Med2015 Jul 01; 82
AB  - Ceftaroline is a broad-spectrum cephalosporin used to treat infections caused by a variety of microorganisms, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Streptococcus pneumoniae. However, it is not active against Pseudomonas aeruginosa, Bacteroides fragilis, and carbapenem-resistant Enterobacteriaceae. Its approved indications include community-acquired bacterial pneumonia and bacterial infections of skin and skin structures. It has also been used off-label to treat osteomyelitis, endocarditis, and meningitis caused by ceftaroline-susceptible organisms.