PT - JOURNAL ARTICLE AU - King, Ashley AU - Quirouet, Adrienne AU - Moore, Courtenay K. TI - Urologic applications of botulinum toxin AID - 10.3949/ccjm.82a.13166 DP - 2015 Jul 01 TA - Cleveland Clinic Journal of Medicine PG - 456--464 VI - 82 IP - 7 4099 - http://www.ccjm.org/content/82/7/456.short 4100 - http://www.ccjm.org/content/82/7/456.full SO - Cleve Clin J Med2015 Jul 01; 82 AB - The neuromuscular blocker botulinum toxin has a wide variety of medical applications, including overactive bladder and neurogenic detrusor overactivity in patients in whom drug therapy fails or is not well tolerated. Botulinum toxin therapy for these conditions has been shown to be safe and effective in several large multicenter randomized controlled trials. Off-label uses in urology include detrusor external sphincter dyssynergia and pelvic pain syndromes.