RT Journal Article SR Electronic T1 Clinical challenges in diagnosing and managing adult hypertension JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP S36 OP S41 DO 10.3949/ccjm.82.s2.06 VO 82 IS 12 suppl 2 A1 Handler, Joel YR 2015 UL http://www.ccjm.org/content/82/12_suppl_2/S36.abstract AB Although there is still no consensus on how to diagnose hypertension, opinion is moving toward incorporating out-of-office blood pressure measurements into the process. The SPRINT trial poses potential opportunities and challenges. Simplified antihypertensive drug regimens incorporating single pill combinations are very effective.