PT - JOURNAL ARTICLE AU - Jennifer Hadam AU - Elie Aoun AU - Kofi Clarke AU - Mary Chester Wasko TI - Managing risks of TNF inhibitors: An update for the internist AID - 10.3949/ccjm.81a.12121 DP - 2014 Feb 01 TA - Cleveland Clinic Journal of Medicine PG - 115--127 VI - 81 IP - 2 4099 - http://www.ccjm.org/content/81/2/115.short 4100 - http://www.ccjm.org/content/81/2/115.full SO - Cleve Clin J Med2014 Feb 01; 81 AB - Tumor necrosis factor (TNF) inhibitors have many beneficial effects, but they also pose infrequent but significant risks, including serious infection and malignancy. These risks can be minimized by judicious patient selection, appropriate screening, careful monitoring during treatment, and close communication between primary care physicians and subspecialists.