TY - JOUR T1 - Acute and critical limb ischemia: When time is limb JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 209 LP - 216 DO - 10.3949/ccjm.81gr.13003 VL - 81 IS - 4 AU - Mehdi H. Shishehbor Y1 - 2014/04/01 UR - http://www.ccjm.org/content/81/4/209.abstract N2 - Acute and critical limb ischemia post significant rates of morbidity and death, and need to be promptly recognized and treated to avoid amputation. Perfusion should be thoroughly assessed using multiple methods, and patients should be considered for revascularization (angioplasty or bypass surgery) to restore blood perfusion. Underlying conditions that need to be assessed and treated include cardiovascular disease, diabetes, and infection. ER -