PT - JOURNAL ARTICLE AU - Lincoff, A. Michael TI - Managing acute coronary syndromes: Decades of progress AID - 10.3949/ccjm.81gr.13002 DP - 2014 Apr 01 TA - Cleveland Clinic Journal of Medicine PG - 233--242 VI - 81 IP - 4 4099 - http://www.ccjm.org/content/81/4/233.short 4100 - http://www.ccjm.org/content/81/4/233.full SO - Cleve Clin J Med2014 Apr 01; 81 AB - In managing acute coronary syndromes, physicians can draw on a large body of evidence from clinical trials. This article reviews clinical trials that inform current standards of practice regarding reperfusion, aggressive vs conservative initial approaches, and the appropriate use of aspirin, dual antiplatelet therapy, glycoprotein IIb/IIIa antagonists, anticoagulants, and statins.