RT Journal Article SR Electronic T1 Managing acute coronary syndromes: Decades of progress JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 233 OP 242 DO 10.3949/ccjm.81gr.13002 VO 81 IS 4 A1 A. Michael Lincoff YR 2014 UL http://www.ccjm.org/content/81/4/233.abstract AB In managing acute coronary syndromes, physicians can draw on a large body of evidence from clinical trials. This article reviews clinical trials that inform current standards of practice regarding reperfusion, aggressive vs conservative initial approaches, and the appropriate use of aspirin, dual antiplatelet therapy, glycoprotein IIb/IIIa antagonists, anticoagulants, and statins.