TY - JOUR T1 - Heart failure in African Americans: Disparities can be overcome JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 301 LP - 311 DO - 10.3949/ccjm.81a.13045 VL - 81 IS - 5 AU - Alok Sharma AU - Monica Colvin-Adams AU - Clyde W. Yancy Y1 - 2014/05/01 UR - http://www.ccjm.org/content/81/5/301.abstract N2 - African Americans are disproportionately affected by heart failure, with a high prevalence at an early age. Hypertension, diabetes, obesity, and chronic kidney disease are all common in African Americans and all predispose to heart failure. Neurohormonal imbalances, endothelial dysfunction, genetic polymorphisms, and socioeconomic factors also contribute. In general, the same evidence-based treatment guidelines that apply to white patients with heart failure also apply to African Americans. However, the combination of hydralazine and isosorbide dinitrate is advised specifically for African Americans. ER -