RT Journal Article SR Electronic T1 Heart failure in African Americans: Disparities can be overcome JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 301 OP 311 DO 10.3949/ccjm.81a.13045 VO 81 IS 5 A1 Alok Sharma A1 Monica Colvin-Adams A1 Clyde W. Yancy YR 2014 UL http://www.ccjm.org/content/81/5/301.abstract AB African Americans are disproportionately affected by heart failure, with a high prevalence at an early age. Hypertension, diabetes, obesity, and chronic kidney disease are all common in African Americans and all predispose to heart failure. Neurohormonal imbalances, endothelial dysfunction, genetic polymorphisms, and socioeconomic factors also contribute. In general, the same evidence-based treatment guidelines that apply to white patients with heart failure also apply to African Americans. However, the combination of hydralazine and isosorbide dinitrate is advised specifically for African Americans.