RT Journal Article SR Electronic T1 Advances in autosomal dominant polycystic kidney disease—2014 and beyond JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 545 OP 556 DO 10.3949/ccjm.81gr.14001 VO 81 IS 9 A1 Braun, William E. YR 2014 UL http://www.ccjm.org/content/81/9/545.abstract AB Autosomal dominant polycystic kidney disease (ADPKD), which frequently leads to end-stage renal disease, currently has no specific drug therapies. Better understanding of its pathogenesis and recent clinical trials have led to more accurate diagnosis of the disease and its manifestations, as well as to promising new approaches to treatment.