TY - JOUR T1 - Why are we doing cardiovascular outcome trials in type 2 diabetes? JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 665 LP - 671 DO - 10.3949/ccjm.81gr.14005 VL - 81 IS - 11 AU - Venu Menon AU - Bhuvnesh Aggarwal Y1 - 2014/11/01 UR - http://www.ccjm.org/content/81/11/665.abstract N2 - Cardiovascular disease is the leading cause of morbidity and death in people with diabetes mellitus. While worsening hyperglycemia is directly associated with poorer outcomes, studies aiming at euglycemia have failed to show an advantage over modest glucose-lowering strategies. Several diabetes drugs that were approved solely on the basis of their glucose-lowering potential were later shown to increase cardiovascular risk. ER -