PT - JOURNAL ARTICLE AU - Xian Wen Jin AU - Laura Lipold AU - Andrea Sikon AU - Ellen Rome TI - Human papillomavirus vaccine: Safe, effective, underused AID - 10.3949/ccjm.80a.12084 DP - 2013 Jan 01 TA - Cleveland Clinic Journal of Medicine PG - 49--60 VI - 80 IP - 1 4099 - http://www.ccjm.org/content/80/1/49.short 4100 - http://www.ccjm.org/content/80/1/49.full SO - Cleve Clin J Med2013 Jan 01; 80 AB - Vaccination against human papillomavirus (HPV) is safe and effective. It is recommended for females age 9 to 26 and for males age 11 to 26, yet vaccination rates are low. We review the host immune response, the data behind the recommendations for HPV vaccination, and the challenges of implementing the vaccination program.