RT Journal Article SR Electronic T1 Human papillomavirus vaccine: Safe, effective, underused JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 49 OP 60 DO 10.3949/ccjm.80a.12084 VO 80 IS 1 A1 Xian Wen Jin A1 Laura Lipold A1 Andrea Sikon A1 Ellen Rome YR 2013 UL http://www.ccjm.org/content/80/1/49.abstract AB Vaccination against human papillomavirus (HPV) is safe and effective. It is recommended for females age 9 to 26 and for males age 11 to 26, yet vaccination rates are low. We review the host immune response, the data behind the recommendations for HPV vaccination, and the challenges of implementing the vaccination program.