PT - JOURNAL ARTICLE AU - Simon W. Lam AU - Seth R. Bauer AU - Jorge A. Guzman TI - Septic shock: The initial moments and beyond AID - 10.3949/ccjm.80a.12002 DP - 2013 Mar 01 TA - Cleveland Clinic Journal of Medicine PG - 175--184 VI - 80 IP - 3 4099 - http://www.ccjm.org/content/80/3/175.short 4100 - http://www.ccjm.org/content/80/3/175.full SO - Cleve Clin J Med2013 Mar 01; 80 AB - Our understanding of the pathophysiology and treatment of sepsis has advanced over the last decade, and evidence-based protocols have improved its outcomes. Here, we review its management in the first hours and afterward, including topics of ongoing study and debate.