RT Journal Article SR Electronic T1 Septic shock: The initial moments and beyond JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 175 OP 184 DO 10.3949/ccjm.80a.12002 VO 80 IS 3 A1 Simon W. Lam A1 Seth R. Bauer A1 Jorge A. Guzman YR 2013 UL http://www.ccjm.org/content/80/3/175.abstract AB Our understanding of the pathophysiology and treatment of sepsis has advanced over the last decade, and evidence-based protocols have improved its outcomes. Here, we review its management in the first hours and afterward, including topics of ongoing study and debate.