TY - JOUR T1 - Septic shock: The initial moments and beyond JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 175 LP - 184 DO - 10.3949/ccjm.80a.12002 VL - 80 IS - 3 AU - Simon W. Lam AU - Seth R. Bauer AU - Jorge A. Guzman Y1 - 2013/03/01 UR - http://www.ccjm.org/content/80/3/175.abstract N2 - Our understanding of the pathophysiology and treatment of sepsis has advanced over the last decade, and evidence-based protocols have improved its outcomes. Here, we review its management in the first hours and afterward, including topics of ongoing study and debate. ER -