PT  - JOURNAL ARTICLE
AU  - Margaret Seton
TI  - Paget disease of bone: Diagnosis and drug therapy
AID  - 10.3949/ccjm.80a.12142
DP  - 2013 Jul 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 452--462
VI  - 80
IP  - 7
4099  - http://www.ccjm.org/content/80/7/452.short
4100  - http://www.ccjm.org/content/80/7/452.full
SO  - Cleve Clin J Med2013 Jul 01; 80
AB  - Paget disease of bone is a focal disorder of aging bone that may be asymptomatic or may present with pain, bowing deformity, fracture, or a nonspecific rheumatic complaint. It is the second most common disease of bone in the elderly after osteoporosis, and the loss of structural integrity in affected bone conveys a risk of fracture. It may occur sporadically or in geographic or familial clusters. This article discusses the prevalence, pathology, workup, and treatment of Paget disease of bone.