RT Journal Article
SR Electronic
T1 Paget disease of bone: Diagnosis and drug therapy
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 452
OP 462
DO 10.3949/ccjm.80a.12142
VO 80
IS 7
A1 Margaret Seton
YR 2013
UL http://www.ccjm.org/content/80/7/452.abstract
AB Paget disease of bone is a focal disorder of aging bone that may be asymptomatic or may present with pain, bowing deformity, fracture, or a nonspecific rheumatic complaint. It is the second most common disease of bone in the elderly after osteoporosis, and the loss of structural integrity in affected bone conveys a risk of fracture. It may occur sporadically or in geographic or familial clusters. This article discusses the prevalence, pathology, workup, and treatment of Paget disease of bone.