PT  - JOURNAL ARTICLE
AU  - Soumya Chatterjee
AU  - Richard Prayson
AU  - Carol Farver
TI  - Antisynthetase syndrome: Not just an inflammatory myopathy
AID  - 10.3949/ccjm.80a.12171
DP  - 2013 Oct 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 655--666
VI  - 80
IP  - 10
4099  - http://www.ccjm.org/content/80/10/655.short
4100  - http://www.ccjm.org/content/80/10/655.full
SO  - Cleve Clin J Med2013 Oct 01; 80
AB  - In recent years, antisynthetase syndrome has been recognized as an important cause of autoimmune inflammatory myopathy in a subset of patients with polymyositis and dermatomyositis. It is associated with serum antibodies to aminoacyl-transfer RNA synthetases and is characterized by a constellation of manifestations, including fever, myositis, interstitial lung disease, “mechanic’s hands,” Raynaud phenomenon, and polyarthritis. Physicians should be familiar with its variety of clinical presentations and should include it in the differential diagnosis in patients presenting with unexplained interstitial lung disease.