RT Journal Article
SR Electronic
T1 Antisynthetase syndrome: Not just an inflammatory myopathy
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 655
OP 666
DO 10.3949/ccjm.80a.12171
VO 80
IS 10
A1 Soumya Chatterjee
A1 Richard Prayson
A1 Carol Farver
YR 2013
UL http://www.ccjm.org/content/80/10/655.abstract
AB In recent years, antisynthetase syndrome has been recognized as an important cause of autoimmune inflammatory myopathy in a subset of patients with polymyositis and dermatomyositis. It is associated with serum antibodies to aminoacyl-transfer RNA synthetases and is characterized by a constellation of manifestations, including fever, myositis, interstitial lung disease, “mechanic’s hands,” Raynaud phenomenon, and polyarthritis. Physicians should be familiar with its variety of clinical presentations and should include it in the differential diagnosis in patients presenting with unexplained interstitial lung disease.