PT - JOURNAL ARTICLE AU - Tehrani, David M. AU - Seto, Arnold H. TI - Third universal definition of myocardial infarction: Update, caveats, differential diagnoses AID - 10.3949/ccjm.80a.12158 DP - 2013 Dec 01 TA - Cleveland Clinic Journal of Medicine PG - 777--786 VI - 80 IP - 12 4099 - http://www.ccjm.org/content/80/12/777.short 4100 - http://www.ccjm.org/content/80/12/777.full SO - Cleve Clin J Med2013 Dec 01; 80 AB - Updated definitions of myocardial infarction (MI) reflect research on measuring cardiac troponin to diagnose MI. Elevations of this biomarker indicate cardiac injury but not always an acute coronary syndrome. Clinical judgment is needed to interpret increasingly sensitive biomarker assays appropriately. Here, we review the new MI definitions and the various causes of elevated troponin to enable physicians to differentiate acute coronary syndromes from other conditions.