RT Journal Article SR Electronic T1 Third universal definition of myocardial infarction: Update, caveats, differential diagnoses JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 777 OP 786 DO 10.3949/ccjm.80a.12158 VO 80 IS 12 A1 Tehrani, David M. A1 Seto, Arnold H. YR 2013 UL http://www.ccjm.org/content/80/12/777.abstract AB Updated definitions of myocardial infarction (MI) reflect research on measuring cardiac troponin to diagnose MI. Elevations of this biomarker indicate cardiac injury but not always an acute coronary syndrome. Clinical judgment is needed to interpret increasingly sensitive biomarker assays appropriately. Here, we review the new MI definitions and the various causes of elevated troponin to enable physicians to differentiate acute coronary syndromes from other conditions.