PT  - JOURNAL ARTICLE
AU  - Khaldoon Shaheen
AU  - M. Chadi Alraies
AU  - Abdul Hamid Alraiyes
AU  - Richard Christie
TI  - Factor V Leiden: How great is the risk of venous thromboembolism?
AID  - 10.3949/ccjm.79a.11072
DP  - 2012 Apr 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 265--272
VI  - 79
IP  - 4
4099  - http://www.ccjm.org/content/79/4/265.short
4100  - http://www.ccjm.org/content/79/4/265.full
SO  - Cleve Clin J Med2012 Apr 01; 79
AB  - The factor V Leiden mutation, the most common inherited cause of thrombophilia, causes a mild hypercoagulable state. We describe a 29-year-old man, heterozygous for factor V Leiden, who developed extensive pulmonary emboli with concomitant bilateral deep venous thrombosis, likely provoked by prolonged immobility during a car trip. We then review the diagnosis, therapy, screening, and prognosis of venous thromboembolism related to factor V Leiden.