RT Journal Article
SR Electronic
T1 Factor V Leiden: How great is the risk of venous thromboembolism?
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 265
OP 272
DO 10.3949/ccjm.79a.11072
VO 79
IS 4
A1 Khaldoon Shaheen
A1 M. Chadi Alraies
A1 Abdul Hamid Alraiyes
A1 Richard Christie
YR 2012
UL http://www.ccjm.org/content/79/4/265.abstract
AB The factor V Leiden mutation, the most common inherited cause of thrombophilia, causes a mild hypercoagulable state. We describe a 29-year-old man, heterozygous for factor V Leiden, who developed extensive pulmonary emboli with concomitant bilateral deep venous thrombosis, likely provoked by prolonged immobility during a car trip. We then review the diagnosis, therapy, screening, and prognosis of venous thromboembolism related to factor V Leiden.