TY - JOUR T1 - Factor V Leiden: How great is the risk of venous thromboembolism? JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 265 LP - 272 DO - 10.3949/ccjm.79a.11072 VL - 79 IS - 4 AU - Khaldoon Shaheen AU - M. Chadi Alraies AU - Abdul Hamid Alraiyes AU - Richard Christie Y1 - 2012/04/01 UR - http://www.ccjm.org/content/79/4/265.abstract N2 - The factor V Leiden mutation, the most common inherited cause of thrombophilia, causes a mild hypercoagulable state. We describe a 29-year-old man, heterozygous for factor V Leiden, who developed extensive pulmonary emboli with concomitant bilateral deep venous thrombosis, likely provoked by prolonged immobility during a car trip. We then review the diagnosis, therapy, screening, and prognosis of venous thromboembolism related to factor V Leiden. ER -