PT - JOURNAL ARTICLE AU - Videtic, Gregory M.M. TI - Locally advanced non–small cell lung cancer: What is the optimal concurrent chemoradiation regimen? AID - 10.3949/ccjm.79.s2.07 DP - 2012 May 01 TA - Cleveland Clinic Journal of Medicine PG - S32--S37 VI - 79 IP - 5 e-suppl 1 4099 - http://www.ccjm.org/content/79/5_e-suppl_1/S32.short 4100 - http://www.ccjm.org/content/79/5_e-suppl_1/S32.full SO - Cleve Clin J Med2012 May 01; 79 AB - The optimal chemoradiation regimen for patients with locally advanced non–small cell lung cancer (NSCLC) has yet to be defined. Disease and patient heterogeneity prevent a “one size fits all” approach to treatment. Concurrent chemoradiation up front is the definitive strategy for patients with unresectable stage III NSCLC; the addition of consolidation chemotherapy following definitive treatment has produced conflicting results with respect to overall survival. Biologic therapies have yet to show value as add-on treatment to chemoradiation.