RT Journal Article SR Electronic T1 Aortic stenosis: Who should undergo surgery, transcatheter valve replacement? JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 487 OP 497 DO 10.3949/ccjm.79a.11043 VO 79 IS 7 A1 Fadi Sawaya A1 James Stewart A1 Vasilis Babaliaros YR 2012 UL http://www.ccjm.org/content/79/7/487.abstract AB Aortic stenosis, the most common valvular disease in the Western world, affects mainly people over age 60. It is characterized by years to decades of slow progression followed by rapid clinical deterioration and a high death rate once symptoms develop. Drug therapy for it remains ineffective, and surgical aortic valve replacement is the only effective long-term treatment. We discuss the indications for this surgery, with an emphasis on controversial conditions in which the indications are less well defined.