PT  - JOURNAL ARTICLE
AU  - Merkel, Peter A.
TI  - Defining disease activity and damage in patients with small-vessel vasculitis
AID  - 10.3949/ccjm.79.s3.03
DP  - 2012 Nov 01
TA  - Cleveland Clinic Journal of Medicine
PG  - S11--S15
VI  - 79
IP  - 11 suppl 3
4099  - http://www.ccjm.org/content/79/11_suppl_3/S11.short
4100  - http://www.ccjm.org/content/79/11_suppl_3/S11.full
SO  - Cleve Clin J Med2012 Nov 01; 79
AB  - The complexity of small-vessel vasculitis requires repeated evaluations of disease activity and damage. Clinical assessment, including regular restaging of disease, is important for management of therapeutic interventions; similarly, assessment tools must be standardized and validated for use in the clinical trial setting. The Outcome Measures in Rheumatology group promotes validated outcomes measures for use in trials. Validated tools for use in clinical trials include the Birmingham Vasculitis Activity Score and the Vasculitis Damage Index. In addition, health-related quality of life assessments underscore the importance of patient-ranked issues in assessing and treating vasculitis. Improvements in the clinical treatment of vasculitis will arise from research that is supported by refined and validated assessment tools