RT Journal Article
SR Electronic
T1 Inflammatory signaling in Alzheimer disease and depression
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP S47
OP S49
DO 10.3949/ccjm.78.s1.08
VO 78
IS 8 suppl 1
A1 Robert Barber
YR 2011
UL http://www.ccjm.org/content/78/8_suppl_1/S47.abstract
AB To help define the relationships among inflammation, Alzheimer disease, and depression, the Texas Alzheimer’s Research Consortium analyzed an array of inflammatory biomarkers in a cohort of patients with Alzheimer disease and in controls. Inflammation severity was highly correlated with earlier age at onset of Alzheimer disease and was also associated with cognitive decline. The relationship between inflammation and depression was not as clear, and it varied with aspects of depression, gender, and the presence of Alzheimer disease.